A CRY in the Night

被引：6

作者：

DeBruyne, Jason P. ^{[1
]}

Hogenesch, John B. ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Pharmacol, Inst Translat Med & Therapeut, Philadelphia, PA 19104 USA

来源：

DEVELOPMENTAL CELL | 2011年 / 20卷 / 02期

关键词：

MAMMALIAN CIRCADIAN CLOCK;

D O I：

10.1016/j.devcel.2011.01.014

中图分类号：

Q2 [细胞生物学];

学科分类号：

071013 [干细胞生物学];

摘要：

CRY1 is essential for normal circadian clock function, but its transcriptional regulation by the clock has not been considered an important feature for its function. However, reporting in Cell, Ukai-Tadenuma et al. (2011) now show that rhythmic Cry1 expression in the early night is critical for clock function.

引用

收藏

页码：144 / 145

页数：2

相关论文

共 8 条

[1]

Rhythmic histone acetylation underlies transcription in the mammalian circadian clock [J].

Etchegaray, JP ;

Lee, C ;

Wade, PA ;

Reppert, SM .

NATURE, 2003, 421 (6919) :177-182

[2]

Cycling of CRYPTOCHROME proteins is not necessary for Circadian-clock function in mammalian fibroblasts [J].

Fan, Yunzhen ;

Hida, Akiko ;

Anderson, Daniel A. ;

Izumo, Mariko ;

Johnson, Carl Hirschie .

CURRENT BIOLOGY, 2007, 17 (13) :1091-1100

[3]

Posttranslational mechanisms regulate the mammalian circadian clock [J].

Lee, C ;

Etchegaray, JP ;

Cagampang, FRA ;

Loudon, ASI ;

Reppert, SM .

CELL, 2001, 107 (07) :855-867

[4]

Stoichiometric Relationship among Clock Proteins Determines Robustness of Circadian Rhythms [J].

Lee, Yongjin ;

Chen, Rongmin ;

Lee, Hyeong-min ;

Lee, Choogon .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2011, 286 (09) :7033-7042

[5]

Coordination of circadian timing in mammals [J].

Reppert, SM ;

Weaver, DR .

NATURE, 2002, 418 (6901) :935-941

[6]

The genetics of mammalian circadian order and disorder: implications for physiology and disease [J].

Takahashi, Joseph S. ;

Hong, Hee-Kyung ;

Ko, Caroline H. ;

McDearmon, Erin L. .

NATURE REVIEWS GENETICS, 2008, 9 (10) :764-775

[7]

System-level identification of transcriptional circuits underlying mammalian circadian clocks [J].

Ueda, HR ;

Hayashi, S ;

Chen, WB ;

Sano, M ;

Machida, M ;

Shigeyoshi, Y ;

Iino, M ;

Hashimoto, S .

NATURE GENETICS, 2005, 37 (02) :187-192

[8]

Delay in Feedback Repression by Cryptochrome 1 Is Required for Circadian Clock Function [J].

Ukai-Tadenuma, Maki ;

Yamada, Rikuhiro G. ;

Xu, Haiyan ;

Ripperger, Juergen A. ;

Liu, Andrew C. ;

Ueda, Hiroki R. .

CELL, 2011, 144 (02) :268-281