Well-Defined Uncharged Polymers with a Sharp UCST in Water and in Physiological Milieu

被引：138

作者：

Glatzel, Stefan ^{[1
]}

Laschewsky, Andre ^{[1
,2
]}

Lutz, Jean-Francois ^{[1
]}

机构：

[1] Fraunhofer Inst Appl Polymer Res, D-14476 Potsdam, Germany

[2] Univ Potsdam, Dept Chem, Potsdam, Germany

来源：

MACROMOLECULES | 2011年 / 44卷 / 02期

关键词：

AQUEOUS-SOLUTIONS; BLOCK-COPOLYMERS; TEMPERATURE-RESPONSE; PHASE-BEHAVIOR; GEL SYSTEMS; POLY(N-ISOPROPYLACRYLAMIDE); METHACRYLATE; LCST; POLYMERIZATION; ASSOCIATION;

D O I：

10.1021/ma102677k

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 [高分子化学与物理];

摘要：

A study was conducted to demonstrate well-defined uncharged polymers with a sharp upper critical solution temperature (UCST) in water and in physiological milieu. The study also described the reversible addition-fragmentation chain transfer (RAFT) homopolymerization of N-acryloylasparaginamide (NAAAM). NAAAM was synthesized in a single step by reacting acryloyl chloride with L-asparaginamide hydrochloride. A series of NAAAM homopolymers of variable chain length were synthesized by RAFT polymerization and the properties of the formed homopolymers in dilute aqueous solutions were studied by turbidimetry. The formed polymers exhibited a well-definedmolecular structure and unprecedented UCST properties in water and in physiological milieu.

引用

页码：413 / 415

页数：3

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