Stem cell factor: Biology and relevance to clinical practice

被引：32

作者：

Smith, MA

Pallister, CJ

Smith, JG

机构：

[1] Royal United Hosp NHS Trust, Dept Haematol, Bath BA1 3NG, Avon, England

[2] Univ W England, Ctr Biomed Res, Bristol BS16 1QY, Avon, England

来源：

ACTA HAEMATOLOGICA | 2001年 / 105卷 / 03期

关键词：

stem cell factor; haemopoiesis; ex vivo; expansion; PBSC mobilisation; aplastic anaemia;

D O I：

10.1159/000046556

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The type III tyrosine kinase receptor c-KIT and its ligand stem cell factor (SCF; also known as KIT ligand, mast cell growth factor and steel factor) are closely involved in the regulation of a wide range of tissues at different stages of life. This review provides an outline of the discovery, structure and expression of SCF and c-KIT but concentrates on their respective roles in the regulation of human haemopoiesis and how this knowledge might be exploited in the clinical setting. Copyright (C) 2001 S. Karger AG, Basel.

引用

收藏

页码：143 / 150

页数：8

相关论文

共 65 条

[11] Stem cell factor and hematopoiesis [J].

Broudy, VC .

BLOOD, 1997, 90 (04) :1345-1364

[12] RETRACTED: RECONSTITUTION OF HEMATOPOIESIS AFTER HIGH-DOSE CHEMOTHERAPY BY AUTOLOGOUS PROGENITOR CELLS GENERATED EX-VIVO (RETRACTED ARTICLE. SEE VOL 345, PG 64, 2001) [J].

BRUGGER, W ;

HEIMFELD, S ;

BERENSON, RJ ;

MERTELSANN, R ;

KANZ, L .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 333 (05) :283-287

[13] A MONOCLONAL-ANTIBODY TO A HUMAN MAST-CELL MYELOID LEUKEMIA-SPECIFIC ANTIGEN BINDS TO NORMAL HEMATOPOIETIC PROGENITOR CELLS AND INHIBITS COLONY FORMATION INVITRO [J].

CAMBARERI, AC ;

ASHMAN, LK ;

COLE, SR ;

LYONS, AB .

LEUKEMIA RESEARCH, 1988, 12 (11-12) :929-+

[14]

CARLOS TM, 1994, BLOOD, V84, P2068

[15]

DUBOIS CM, 1994, BLOOD, V83, P3138

[16] STEEL FACTOR INFLUENCES THE DISTRIBUTION AND ACTIVITY OF MURINE HEMATOPOIETIC STEM-CELLS INVIVO [J].

FLEMING, WH ;

ALPERN, EJ ;

UCHIDA, N ;

IKUTA, K ;

WEISSMAN, IL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (08) :3760-3764

[17] A MURINE MONOCLONAL-ANTIBODY SPECIFIC FOR A CELL-SURFACE ANTIGEN EXPRESSED BY A SUBGROUP OF HUMAN MYELOID LEUKEMIAS [J].

GADD, SJ ;

ASHMAN, LK .

LEUKEMIA RESEARCH, 1985, 9 (11) :1329-1336

[18] c-kit proto-oncogene exon 8 in-frame deletion plus insertion mutations in acute myeloid leukaemia [J].

Gari, M ;

Goodeve, A ;

Wilson, G ;

Winship, P ;

Langabeer, S ;

Linch, D ;

Vandenberghe, E ;

Peake, I ;

Reilly, J .

BRITISH JOURNAL OF HAEMATOLOGY, 1999, 105 (04) :894-900

[19] Peripheral blood progenitor cell mobilization using stem cell factor in combination with filgrastim in breast cancer patients [J].

Glaspy, JA ;

Shpall, EJ ;

LeMaistre, CF ;

Briddell, RA ;

Menchaca, DM ;

Turner, SA ;

Lill, M ;

Chap, L ;

Jones, R ;

Wiers, MD ;

Sheridan, WP ;

McNiece, IK .

BLOOD, 1997, 90 (08) :2939-2951

[20] Ex vivo expansion of CD34+/CD41+late progenitors from enriched peripheral blood CD34+cells [J].

Halle, P ;

Rouzier, C ;

Kanold, J ;

Boiret, N ;

Rapatel, C ;

Mareynat, G ;

Tchirkov, A ;

Berger, M ;

Travade, P ;

Bonhomme, J ;

Deméocq, F .

ANNALS OF HEMATOLOGY, 2000, 79 (01) :13-19

← 1 2 3 4 5 6 7 →