Lipase-mediated synthesis of the enantiomeric forms of 4,5-epoxy-4,5-dihydro-α-ionone and 5,6-epoxy-5,6-dihydro-β-ionone.: A new direct access to enantiopure (R)- and (S)-α-ionone

被引：35

作者：

Aleu, J ^{[1
]}

Brenna, E ^{[1
]}

Fuganti, C ^{[1
]}

Serra, S ^{[1
]}

机构：

[1] Politecn Milan, Dipartimento Chim, I-20131 Milan, Italy

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 03期

关键词：

D O I：

10.1039/a808780f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereoselective lipase-mediated esterifications of epoxy-alpha-ionol 5 and epoxy-beta-ionol 9 afforded suitable precursors of the enantiomers of the corresponding oxidised derivatives epoxy-alpha-ionone 3 and epoxy-beta-ionone 4. An interesting: development of this work is the easy conversion of enantiopure 3a and 3b into highly valuable enantiopure (S)- and (R)-ionone (1a and 1b) via a mild deoxygenation reaction.

引用

页码：271 / 278

页数：8

共 25 条

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