Upstream-downstream: CD28 cosignaling pathways and T cell function

[51] 2-STEP TCR-ZETA/CD3-CD4 AND CD28 SIGNALING IN T-CELLS - SH2/SH3 DOMAINS, PROTEIN-TYROSINE AND LIPID KINASES [J]. IMMUNOLOGY TODAY, 1994, 15 (05): : 225 - 234

[52] T-CELL ANTIGEN CD28 BINDS TO THE GRB-2/SOS COMPLEX, REGULATORS OF P21(RAS) [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (04) : 1044 - 1050

[53] DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE [J]. SCIENCE, 1993, 261 (5121) : 609 - 612

[54] JNK IS INVOLVED IN SIGNAL INTEGRATION DURING COSTIMULATION OF T-LYMPHOCYTES [J]. CELL, 1994, 77 (05) : 727 - 736

[55] DISTINCT ROLES FOR THE COSTIMULATORY LIGANDS B7-1 AND B7-2 IN T-HELPER CELL-DIFFERENTIATION [J]. CELL, 1995, 81 (07) : 979 - 982

[56] LOSS OF CTLA-4 LEADS TO MASSIVE LYMPHOPROLIFERATION AND FATAL MULTIORGAN TISSUE DESTRUCTION, REVEALING A CRITICAL NEGATIVE REGULATORY ROLE OF CTLA-4 [J]. IMMUNITY, 1995, 3 (05) : 541 - 547

[57] TUMOR REJECTION AFTER DIRECT COSTIMULATION OF CD8+ T-CELLS BY B7-TRANSFECTED MELANOMA-CELLS [J]. SCIENCE, 1993, 259 (5093) : 368 - 370

[58] STIMULATION OF CD28 TRIGGERS AN ASSOCIATION BETWEEN CD28 AND PHOSPHATIDYLINOSITOL 3-KINASE IN JURKAT T-CELLS [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (03) : 1071 - 1076

[59] TRUITT KE, 1995, J IMMUNOL, V155, P4702

[60] BOTH CD28 LIGANDS CD80 (B7-1) AND CD86 (B7-2) ACTIVATE PHOSPHATIDYLINOSITOL 3-KINASE, AND WORTMANNIN REVEALS HETEROGENEITY IN THE REGULATION OF T-CELL IL-2 SECRETION [J]. INTERNATIONAL IMMUNOLOGY, 1995, 7 (06) : 957 - 966

[51] 2-STEP TCR-ZETA/CD3-CD4 AND CD28 SIGNALING IN T-CELLS - SH2/SH3 DOMAINS, PROTEIN-TYROSINE AND LIPID KINASES [J]. IMMUNOLOGY TODAY, 1994, 15 (05): : 225 - 234

[52] T-CELL ANTIGEN CD28 BINDS TO THE GRB-2/SOS COMPLEX, REGULATORS OF P21(RAS) [J]. EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (04) : 1044 - 1050

[53] DIFFERENTIAL T-CELL COSTIMULATORY REQUIREMENTS IN CD28-DEFICIENT MICE [J]. SCIENCE, 1993, 261 (5121) : 609 - 612

[54] JNK IS INVOLVED IN SIGNAL INTEGRATION DURING COSTIMULATION OF T-LYMPHOCYTES [J]. CELL, 1994, 77 (05) : 727 - 736

[55] DISTINCT ROLES FOR THE COSTIMULATORY LIGANDS B7-1 AND B7-2 IN T-HELPER CELL-DIFFERENTIATION [J]. CELL, 1995, 81 (07) : 979 - 982

[56] LOSS OF CTLA-4 LEADS TO MASSIVE LYMPHOPROLIFERATION AND FATAL MULTIORGAN TISSUE DESTRUCTION, REVEALING A CRITICAL NEGATIVE REGULATORY ROLE OF CTLA-4 [J]. IMMUNITY, 1995, 3 (05) : 541 - 547

[57] TUMOR REJECTION AFTER DIRECT COSTIMULATION OF CD8+ T-CELLS BY B7-TRANSFECTED MELANOMA-CELLS [J]. SCIENCE, 1993, 259 (5093) : 368 - 370

[58] STIMULATION OF CD28 TRIGGERS AN ASSOCIATION BETWEEN CD28 AND PHOSPHATIDYLINOSITOL 3-KINASE IN JURKAT T-CELLS [J]. JOURNAL OF EXPERIMENTAL MEDICINE, 1994, 179 (03) : 1071 - 1076

[59] TRUITT KE, 1995, J IMMUNOL, V155, P4702

[60] BOTH CD28 LIGANDS CD80 (B7-1) AND CD86 (B7-2) ACTIVATE PHOSPHATIDYLINOSITOL 3-KINASE, AND WORTMANNIN REVEALS HETEROGENEITY IN THE REGULATION OF T-CELL IL-2 SECRETION [J]. INTERNATIONAL IMMUNOLOGY, 1995, 7 (06) : 957 - 966