Contribution of a novel gene, rpeA, encoding a putative autotransporter adhesin to intestinal colonization by rabbit-specific enteropathogenic Eschetichia coli

被引:14
作者
Leyton, Denisse L.
Adams, Louise M.
Kelly, Michelle
Sloan, Joan
Tauschek, Marija
Robins-Browne, Roy M.
Hartland, Elizabeth L. [1 ]
机构
[1] Monash Univ, Dept Microbiol, Australian Bacterial Pathogenesis Program, Monash, Vic 3800, Australia
[2] Univ Melbourne, Dept Microbiol, Australian Bacterial Pathogenesis Program, Melbourne, Vic, Australia
[3] Royal Childrens Hosp, Murdoch Childrens Res Inst, Microbiol Res Unit, Parkville, Vic 3052, Australia
关键词
D O I
10.1128/IAI.00972-06
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Rabbit-specific enteropathogenic Escherichia coli (REPEC) is an attaching and effacing pathogen of young rabbits. Using signature-tagged mutagenesis, we identified several known colonization factors of REPEC as well as a gene predicted to encode a novel autotransporter protein. This novel gene was termed rpeA for REPEC plasmid-encoded autotransporter.
引用
收藏
页码:4664 / 4669
页数:6
相关论文
共 20 条
[1]   Identification and characterization of a K88- and CS31A-like operon of a rabbit enteropathogenic Escherichia coli strain which encodes fimbriae involved in the colonization of rabbit intestine [J].
Adams, LM ;
Simmons, CP ;
Rezmann, L ;
Strugnell, RA ;
RobinsBrowne, RM .
INFECTION AND IMMUNITY, 1997, 65 (12) :5222-5230
[2]   SEPA, THE MAJOR EXTRACELLULAR PROTEIN OF SHIGELLA-FLEXNERI - AUTONOMOUS SECRETION AND INVOLVEMENT IN TISSUE INVASION [J].
BENJELLOUNTOUIMI, Z ;
SANSONETTI, PJ ;
PARSOT, C .
MOLECULAR MICROBIOLOGY, 1995, 17 (01) :123-135
[3]   One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products [J].
Datsenko, KA ;
Wanner, BL .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (12) :6640-6645
[4]   Adhesive factor/rabbit 2, a new fimbrial adhesin and a virulence factor from Escherichia coli O103, a serogroup enteropathogenic for rabbits [J].
Fiederling, F ;
Boury, M ;
Petit, C ;
Milon, A .
INFECTION AND IMMUNITY, 1997, 65 (02) :847-851
[5]   Enteropathogenic and enterohaemorrhagic Escherichia coli:: more subversive elements [J].
Frankel, G ;
Phillips, AD ;
Rosenshine, I ;
Dougan, G ;
Kaper, JB ;
Knutton, S .
MOLECULAR MICROBIOLOGY, 1998, 30 (05) :911-921
[6]  
GEME JW, 2000, J BACTERIOL, V182, P6005
[7]   Characterization of pic, a secreted protease of Shigella flexneri and enteroaggregative Escherichia coli [J].
Henderson, IR ;
Czeczulin, J ;
Eslava, C ;
Noriega, F ;
Nataro, JP .
INFECTION AND IMMUNITY, 1999, 67 (11) :5587-5596
[8]  
Henderson IR, 2000, TRENDS MICROBIOL, V8, P529, DOI 10.1016/S0966-842X(00)01853-9
[9]   The Haemophilus influenzae Hap serine protease promotes adherence and microcolony formation, potentiated by a soluble host protein [J].
Hendrixson, DR ;
St Geme, JW .
MOLECULAR CELL, 1998, 2 (06) :841-850
[10]   Structural determinants of processing and secretion of the Haemophilus influenzae Hap protein [J].
Hendrixson, DR ;
delaMorena, ML ;
Stathopoulos, C ;
StGeme, JW .
MOLECULAR MICROBIOLOGY, 1997, 26 (03) :505-518