Neurobehavioral and neuropsychiatric symptoms in Alzheimer's disease - Characteristics and treatment

被引：123

作者：

Chung, JA

Cummings, JL

机构：

[1] Univ Calif Los Angeles, Sch Med, Dept Neurol, Los Angeles, CA 90024 USA

[2] Univ Calif Los Angeles, Sch Med, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA

来源：

NEUROLOGIC CLINICS | 2000年 / 18卷 / 04期

关键词：

D O I：

10.1016/S0733-8619(05)70228-0

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Neuropsychiatric symptoms are common in Alzheimer's disease. Personality changes, mood disturbance, and psychosis are frequently seen and may coexist in the same patient. Neuropsychiatric symptoms may signal the onset of disease and often fluctuate and recur. These symptoms are associated with a more rapid cognitive and functional decline that can lead to institutionalization. Cholinergic therapy, disease-modifying therapy, and psychotropic medications can improve these symptoms.

引用

页码：829 / +

页数：19

共 93 条

[81]

SULTZER DL, 1995, J NEUROPSYCH CLIN N, V7, P476

[82]

Sultzer DL, 1997, AM J GERIAT PSYCHIAT, V5, P60

[83] A double-blind, randomized, fixed-dose trial of fluoxetine vs. amitriptyline in the treatment of major depression complicating Alzheimer's disease [J].