Tunable imaging of cells labeled with MRI-PARACEST agents

被引：129

作者：

Aime, S ^{[1
]}

Carrera, C ^{[1
]}

Delli Castelli, D ^{[1
]}

Crich, SG ^{[1
]}

Terreno, E ^{[1
]}

机构：

[1] Dipartimento Chim IFM, I-10125 Turin, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 12期

关键词：

imaging agents; lanthanides; magnetic properties; proton exchange; saturation transfer;

D O I：

10.1002/anie.200462566

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) Cell-tracking experiments by MRI are possible with a novel class of Tb and Eu paramagnetic imaging agents, with which contrast is generated upon irradiation at a specific frequency (see picture). Middle: A) unlabeled; B) Tb-labeled; C) Eu-labeled; D) Tb- and Eu-labeled cells. Left: irradiation at ± 180 kHz (Tb-agent-specific). Right: irradiation at ± 15 kHz (Eu-agent-specific). © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

收藏

页码：1813 / 1815

页数：3

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