Solubilization and release properties of PEGylated diaminobutane poly(propylene imine) dendrimers

被引：56

作者：

Sideratou, Z ^{[1
]}

Tsiourvas, D ^{[1
]}

Paleos, CM ^{[1
]}

机构：

[1] NCSR Demokritos, Inst Nucl Phys, GR-15310 Athens, Greece

来源：

JOURNAL OF COLLOID AND INTERFACE SCIENCE | 2001年 / 242卷 / 01期

关键词：

PEGylated dendrimers; drug delivery; fluorescence spectroscopy; pyrene; betamethasone corticosteroids;

D O I：

10.1006/jcis.2001.7787

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

PEGylated diaminobutane poly(propylene imine) dendrimers were investigated as prospective drug delivery systems. Solubilization and release properties of these dendrimeric derivatives were investigated by fluorescence spectroscopy by employing pyrene as probe. The prospective application of the same dendrimers as drug carriers was first evaluated by incorporating within their interior sufficient concentrations of betamethasone corticosteroids. (C) 2001 Academic Press.

引用

页码：272 / 276

页数：5

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