Reduction of interstitial fluid pressure after TNF-alpha treatment of three human melanoma xenografts

被引：96

作者：

Kristensen, CA

Nozue, M

Boucher, Y

Jain, RK

机构：

[1] Edwin L Steele Laboratory, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114

来源：

BRITISH JOURNAL OF CANCER | 1996年 / 74卷 / 04期

关键词：

tumour necrosis factor-alpha; interstitial fluid pressure; melanoma xenograft; blood pressure;

D O I：

10.1038/bjc.1996.397

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Tumour necrosis factor-alpha (TNF-alpha) reduced the interstitial fluid pressure (IFP) to 54-64% (P<0.05) and the mean arterial blood pressure (MABP) to 70% (P<0.01) of control values after 5 h in three human melanoma tumour lines transplanted to nude mice.

引用

收藏

页码：533 / 536

页数：4

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