Prothrombotic coagulation abnormalities in patients with newly diagnosed multiple myeloma

被引：107

作者：

Auwerda, Johannes J. A. ^{[1
,2
]}

Sonneveld, Pieter ^{[1
]}

de Maat, Monica P. M. ^{[1
]}

Leebeek, Frank W. G. ^{[1
]}

机构：

[1] Erasmus MC, Dept Haematol, Rotterdam, Netherlands

[2] Ikazia Hosp, Dept Internal Med, Rotterdam, Netherlands

来源：

HAEMATOLOGICA | 2007年 / 92卷 / 02期

关键词：

newly diagnosed multiple myeloma; coagulation abnormalities; vWF; factor VIII; antiphospholipid antibodies; protein S;

D O I：

10.3324/haematol.10454

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Prothrombotic coagulation abnormalities were analyzed in patients with untreated multiple myeloma. Increases in factor VIII, in von Willebrand factor and a decrease in protein S were observed and these changes were strongly associated with disease stage. No difference in baseline coagulation parameters was found between patients with and without subsequent venous thromboembolism.

引用

页码：279 / 280

页数：2

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