2-Alkylindoles via palladium-catalyzed reductive cyclization of ethyl 3-(o-trifluoroacetamidophenyl)-1-propargyl carbonates

被引：26

作者：

Ambrogio, Ilaria ^{[1
]}

Cacchi, Sandro ^{[1
]}

Fabrizi, Giancarlo ^{[1
]}

机构：

[1] Univ Rome Studi La Sapienza, Dipartimento Chim & Tecnol Sostanze Biologicament, I-00185 Rome, Italy

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 43期

关键词：

alkylindoles; cyclization; palladium; alkynes; propargyl esters;

D O I：

10.1016/j.tetlet.2007.07.213

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction of ethyl 3-(o-trifluoroacetamidophenyl)-l-propargyl carbonates with formate anions in the presence of Pd(PPh3)4 affords 2-alkylindoles in good to excellent yields. (C) 2007 Elsevier Ltd. All rights reserved.

引用

页码：7721 / 7725

页数：5

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