Endocytic recycling

被引:1466
作者
Maxfield, FR [1 ]
McGraw, TE [1 ]
机构
[1] Cornell Univ, Weill Med Coll, Dept Biochem, New York, NY 10021 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1038/nrm1315
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
After endocytosis, most membrane proteins and lipids return to the cell surface, but some membrane components are delivered to late endosomes or the Golgi. We now understand that the pathways taken by internalized molecules that eventually recycle to the cell surface can be surprisingly complex and can involve a series of sorting events that occur in several organelles. The molecular basis for many of these sorting processes is only partly understood.
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页码:121 / 132
页数:12
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