Highly chemo- and regioselective intermolecular cyclotrimerization of alkynes catalyzed by cationic rhodium(I)/modified BINAP

被引：131

作者：

Tanaka, K ^{[1
]}

Shirasaka, K ^{[1
]}

机构：

[1] Tokyo Univ Agr & Technol, Dept Appl Chem, Koganei, Tokyo 1848588, Japan

来源：

ORGANIC LETTERS | 2003年 / 5卷 / 24期

关键词：

D O I：

10.1021/ol035963s

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cationic rhodium(I)/modified BINAP complexes are effective catalysts for highly regioselective intermolecular cyclotrimerization of terminal alkynes and highly chemo- and regloselective intermolecular cocyclotrimerization of diethyl acetylenedicarboxylate (DEAD) and terminal alkynes. It is a noteworthy example of intermolecular cocyclotrimerization of two different alkynes in terms of catalytic activity, chemo- and regloselectivity, scope of substrates, and ease of operation. The wide applicability of this new cocyclotrimerization procedure is demonstrated in the one-step synthesis of [6]metacyclophane.

引用

页码：4697 / 4699

页数：3

共 41 条

[1]

[Anonymous], [No title captured], Patent No. [EP 0850945, 0850945]

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