A model complex of a possible intermediate in the mechanism of action of peptide deformylase:: first example of an (N2S)zinc(II)-formate complex

被引：30

作者：

Chang, SC

Sommer, RD

Rheingold, AL

Goldberg, DP

机构：

[1] Johns Hopkins Univ, Dept Chem, Baltimore, MD 21218 USA

[2] Univ Delaware, Dept Chem & Biochem, Newark, DE 19716 USA

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 22期

关键词：

D O I：

10.1039/b106865m

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and crystallographic characterization of a new (N2S) zinc-alkyl complex and (N2S) zinc-formate complex is described; the bonding mode of the formate complex has implications for the mechanism of action of the enzyme peptide deformylase.

引用

页码：2396 / 2397

页数：2

共 15 条

[11] MONOMERIC ALKYL AND HYDRIDE DERIVATIVES OF ZINC SUPPORTED BY POLY(PYRAZOLYL)HYDROBORATO LIGATION - SYNTHETIC, STRUCTURAL, AND REACTIVITY STUDIES [J].