Complexity in biological signaling systems

被引：437

作者：

Weng, GZ

Bhalla, US

Iyengar, R

机构：

[1] CUNY Mt Sinai Sch Med, Dept Pharmacol, New York, NY 10029 USA

[2] Univ Agr Sci Bangalore, Natl Ctr Biol Sci, Bangalore 560065, Karnataka, India

来源：

SCIENCE | 1999年 / 284卷 / 5411期

关键词：

D O I：

10.1126/science.284.5411.92

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Biological signaling pathways interact with one another to form complex networks. Complexity arises from the Large number of components, many with isoforms that have partially overlapping functions; from the connections among components; and from the spatial relationship between components. The origins of the complex behavior of signaling networks and analytical approaches to deal with the emergent complexity are discussed here.

引用

页码：92 / 96

页数：5

共 29 条

[1] PROTEIN HISTIDINE KINASES AND SIGNAL-TRANSDUCTION IN PROKARYOTES AND EUKARYOTES [J].