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Exercise and cardiovascular health - Get active to "AKTivate" your endothelial nitric oxide synthase

被引：48
作者：
Dimmeler, S [1 ]
Zeiher, AM [1 ]
机构：
[1] Goethe Univ Frankfurt, Dept Internal Med 4, Div Mol Cardiol, D-60590 Frankfurt, Germany
来源：
CIRCULATION | 2003年 / 107卷 / 25期
关键词：
editorials; nitric oxide synthase; exercise; endothelium; signal transduction;
D O I：
10.1161/01.CIR.0000074244.82874.A0
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：3118 / 3120
页数：3
相关论文
共 25 条
  • [1] Compensatory phosphorylation and protein-protein interactions revealed by loss of function and gain of function mutants of multiple-serine phosphorylation sites in endothelial nitric-oxide synthase
    Bauer, PM
    Fulton, D
    Boo, YC
    Sorescu, GP
    Kemp, BE
    Jo, H
    Sessa, WC
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (17) : 14841 - 14849
  • [2] Shear stress stimulates phosphorylation of eNOS at Ser635 by a protein kinase A-dependent mechanism
    Boo, YC
    Hwang, J
    Sykes, M
    Michell, BJ
    Kemp, BE
    Lum, H
    Jo, H
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2002, 283 (05): : H1819 - H1828
  • [3] Shear stress stimulates phosphorylation of endothelial nitric-oxide synthase at Ser1179 by Akt-independent mechanisms -: Role of protein kinase A
    Boo, YC
    Sorescu, G
    Boyd, N
    Shiojima, L
    Walsh, K
    Du, J
    Jo, HJ
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (05) : 3388 - 3396
  • [4] AMP-activated protein kinase phosphorylation of endothelial NO synthase
    Chen, ZP
    Mitchelhill, KI
    Michell, BJ
    Stapleton, D
    Rodriguez-Crespo, I
    Witters, LA
    Power, DA
    de Montellano, PRO
    Kemp, BE
    [J]. FEBS LETTERS, 1999, 443 (03) : 285 - 289
  • [5] Akt takes center stage in angiogenesis signaling
    Dimmeler, S
    Zeiher, AM
    [J]. CIRCULATION RESEARCH, 2000, 86 (01) : 4 - 5
  • [6] Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
    Dimmeler, S
    Fleming, I
    Fisslthaler, B
    Hermann, C
    Busse, R
    Zeiher, AM
    [J]. NATURE, 1999, 399 (6736) : 601 - 605
  • [7] HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway
    Dimmeler, S
    Aicher, A
    Vasa, M
    Mildner-Rihm, C
    Adler, K
    Tiemann, M
    Rütten, H
    Fichtlscherer, S
    Martin, H
    Zeiher, AM
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2001, 108 (03) : 391 - 397
  • [8] Feron O, 2001, CIRC RES, V88, P129
  • [9] Fisslthaler B, 2000, ACTA PHYSIOL SCAND, V168, P81
  • [10] Phosphorylation of Thr495 regulates Ca2+/calmodulin-dependent endothelial nitric oxide synthase activity
    Fleming, I
    Fisslthaler, B
    Dimmeler, S
    Kemp, BE
    Busse, R
    [J]. CIRCULATION RESEARCH, 2001, 88 (11) : E68 - E75
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