A rapid parallel synthesis of 2-dialkylamino-4H-imidazolin-4-ones

被引：29

作者：

Ding, MW ^{[1
]}

Sun, Y ^{[1
]}

Yang, SJ ^{[1
]}

Liu, XP ^{[1
]}

Liu, ZJ ^{[1
]}

机构：

[1] Cent China Normal Univ, Inst Organ Synth, Wuhan 430079, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2003年 / 33卷 / 10期

基金：

中国国家自然科学基金;

关键词：

4H-imidazolin-4-ones; Aza-Wittig reaction; parallel synthesis;

D O I：

10.1081/SCC-120018926

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2-Dialkylamino-4H-imidazolin-4-ones 6 were rapidly synthesized by a solution-phase parallel synthetic method, which includes Aza-Wittig reaction of iminophosphorane 3 with aromatic isocynate to give carbodiimide 4 and subsequent reaction of 4 with various aliphatic secondary amine in a parallel fashion.

引用

页码：1651 / 1658

页数：8

共 15 条

[11] 6-PI-ELECTROCYCLIZATION OF AZAHEXA-1,3,5-TRIENES - A NEW ENTRY TO A REGIOSPECIFIC SYNTHESIS OF 3-ARYL(HETEROARYL)PYRIDINES [J].

MOLINA, P ;

PASTOR, A ;

VILAPLANA, MJ .

TETRAHEDRON, 1993, 49 (35) :7769-7778

[12]

Okazaki T, 1998, CHEM PHARM BULL, V46, P777

[13] Utility of complementary molecular reactivity and molecular recognition (CMR/R) technology and polymer-supported reagents in the solution-phase synthesis of heterocyclic carboxamides [J].

Parlow, JJ ;

Mischke, DA ;

Woodard, SS .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (17) :5908-5919

[14]

PILKINGTON BL, 1999, Patent No. 2329180

[15]

1997, Patent No. 5599829

← 1 2 →