Sialorrhea in Parkinson's disease: A review

被引：91

作者：

Chou, Kelvin L. ^{[1
]}

Evatt, Marian ^{[2
]}

Hinson, Vanessa ^{[3
]}

Kompoliti, Katie ^{[4
]}

机构：

[1] Brown Univ, Warren Alpert Med Sch, Dept Clin Neurosci, Providence, RI 02912 USA

[2] Emory Univ, Sch Med, Dept Neurol, Atlanta, GA 30322 USA

[3] Med Univ S Carolina, Dept Neurosci, Charleston, SC 29425 USA

[4] Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USA

来源：

MOVEMENT DISORDERS | 2007年 / 22卷 / 16期

关键词：

sialorrhea; drooling; Parkinson's disease; anticholinergics; botulinum toxin;

D O I：

10.1002/mds.21646

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

A significant number of patients with Parkinson's disease (PD) experience sialorrhea. This problem can cause social embarrassment, and because saliva pools in the mouth, may lead to aspiration pneumonia. Sialorrhea in PD is thought to be caused by impaired or infrequent swallowing, rather than hypersecretion. Oral medications, botulinum toxin injections, surgical interventions, radiotherapy, speech therapy, and trials of devices may be used to treat sialorrhea in PD, but few controlled trials have been published. This article reviews current knowledge regarding the frequency, etiology, assessment, and treatment of sialorrhea in PD. (c) 2007 Movement Disorder Society

引用

页码：2306 / 2313

页数：8

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