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Molecular variants of hepatitis B virus

被引：17
作者：
Carman, WF
机构：
来源：
CLINICS IN LABORATORY MEDICINE | 1996年 / 16卷 / 02期
关键词：
D O I：
10.1016/S0272-2712(18)30277-4
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
Variation in the genome of hepatitis B virus has been associated with a number of clinical parameters, but there is a paucity of functional data to show a causal relationship. For example, variants of the core and X genes have been linked with the pathogenesis of chronic hepatitis, viral replication efficiency, and serologically negative infections, among other observations. Variants of the surface antigen are linked with infection after vaccination, infection of liver grafts in patients undergoing immunotherapy, and samples that react poorly in diagnostic assays.
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页码：407 / &
页数：23
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