Cause, Pathogenesis, and Treatment of Nonalcoholic Steatohepatitis

被引：1208

作者：

Diehl, Anna M. ^{[1
]}

Day, Christopher ^{[2
]}

机构：

[1] Duke Univ, Dept Med, Durham, NC USA

[2] Newcastle Univ, Med Sch, Newcastle Upon Tyne, Tyne & Wear, England

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2017年 / 377卷 / 21期

关键词：

FATTY LIVER-DISEASE; UNITED-STATES; HEPATOCELLULAR-CARCINOMA; HEPATIC-FIBROSIS; GENETIC-FACTORS; RISK; OBESITY; MICE; OUTCOMES; AXIS;

D O I：

10.1056/NEJMra1503519

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

[No abstract available]

引用

页码：2063 / 2072

页数：10

共 59 条

[1]

Nonalcoholic Fatty Liver Disease Increases Risk of Death Among Patients With Diabetes: A Community-Based Cohort Study [J].

Adams, Leon A. ;

Harmsen, Scott ;

St Sauver, Jennifer L. ;

Charatcharoenwitthaya, Phunchai ;

Enders, Felicity B. ;

Therneau, Terry ;

Angulo, Paul .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2010, 105 (07) :1567-1573

[2]

Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease [J].

Angulo, Paul ;

Kleiner, David E. ;

Dam-Larsen, Sanne ;

Adams, Leon A. ;

Bjornsson, Einar S. ;

Charatcharoenwitthaya, Phunchai ;

Mills, Peter R. ;

Keach, Jill C. ;

Lafferty, Heather D. ;

Stahler, Alisha ;

Haflidadottir, Svanhildur ;

Bendtsen, Flemming .

GASTROENTEROLOGY, 2015, 149 (02) :389-+

[3]

Fibrosis in Nonalcoholic Fatty Liver Disease: Mechanisms and Clinical Implications [J].

Angulo, Paul ;

Machado, Mariana Verdelho ;

Diehl, Anna Mae .

SEMINARS IN LIVER DISEASE, 2015, 35 (02) :132-145

[4]

Genetic Factors That Affect Risk of Alcoholic and Nonalcoholic Fatty Liver Disease [J].

Anstee, Quentin M. ;

Seth, Devanshi ;

Day, Christopher P. .

GASTROENTEROLOGY, 2016, 150 (08) :1728-+

[5]

Innate Immunity and Inflammation in NAFLD/NASH [J].

Arrese, Marco ;

Cabrera, Daniel ;

Kalergis, Alexis M. ;

Feldstein, Ariel E. .

DIGESTIVE DISEASES AND SCIENCES, 2016, 61 (05) :1294-1303

[6]

Body mass index in childhood and adult risk of primary liver cancer [J].

Berentzen, Tina Landsvig ;

Gamborg, Michael ;

Holst, Claus ;

Sorensen, Thorkild I. A. ;

Baker, Jennifer L. .

JOURNAL OF HEPATOLOGY, 2014, 60 (02) :325-330

[7]

New advances of DNA methylation in liver fibrosis, with special emphasis on the crosstalk between microRNAs and DNA methylation machinery [J].

Bian, Er-Bao ;

Zhao, Bing ;

Huang, Cheng ;

Wang, Hua ;

Meng, Xiao-Ming ;

Wu, Bao-Ming ;

Ma, Tao-Tao ;

Zhang, Lei ;

Lv, Xiong-Wen ;

Li, Jun .

CELLULAR SIGNALLING, 2013, 25 (09) :1837-1844

[8]

The Severity of Nonalcoholic Fatty Liver Disease Is Associated With Gut Dysbiosis and Shift in the Metabolic Function of the Gut Microbiota [J].

Boursier, Jerome ;

Mueller, Olaf ;

Barret, Matthieu ;

Machado, Mariana ;

Fizanne, Lionel ;

Araujo-Perez, Felix ;

Guy, Cynthia D. ;

Seed, Patrick C. ;

Rawls, John F. ;

David, Lawrence A. ;

Hunault, Gilles ;

Oberti, Frederic ;

Cales, Paul ;

Diehl, Anna Mae .

HEPATOLOGY, 2016, 63 (03) :764-775

[9]

NASH: A glance at the landscape of pharmacological treatment [J].

Brodosi, Lucia ;

Marchignoli, Francesca ;

Petroni, Maria Letizia ;

Marchesini, Giulio .

ANNALS OF HEPATOLOGY, 2016, 15 (05) :673-681

[10]

Frequency and Outcomes of Liver Transplantation for Nonalcoholic Steatohepatitis in the United States [J].

Charlton, Michael R. ;

Burns, Justin M. ;

Pedersen, Rachel A. ;

Watt, Kymberly D. ;

Heimbach, Julie K. ;

Dierkhising, Ross A. .

GASTROENTEROLOGY, 2011, 141 (04) :1249-1253

← 1 2 3 4 5 6 →