Microfluidic synthesis of reversibly swelling porous polymeric microcapsules with controlled morphology

被引：18

作者：

Abraham, Sinoj ^{[1
]}

Park, Yun Hwan ^{[1
]}

Lee, Jin Kyu ^{[1
]}

Ha, Chang-Sik ^{[1
]}

Kim, Il ^{[1
]}

机构：

[1] Pusan Natl Univ, Dept Polymer Sci & Engn, Pusan 609735, South Korea

来源：

ADVANCED MATERIALS | 2008年 / 20卷 / 11期

关键词：

D O I：

10.1002/adma.200700456

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Porous microcapsules formed from polymer-peptide conjugated macromolecules (see figure) are synthesized by the innovative conjunction of microfluidics with block copolymer self-assembly in flow- focusing microchannel. Reversibility of surface nanopores and encapsulation efficiency is investigated in detail.

引用

页码：2177 / +

页数：7

共 79 条

[1] Self-assembly of star-shaped polystyrene-block-polypeptide copolymers synthesized by the combination of atom transfer radical polymerization and ring-opening living polymerization of α-amino acid-N-carboxyanhydrides [J].

Abraham, S ;

Ha, CS ;

Kim, I .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2006, 44 (09) :2774-2783

[2] A facile preparative method for aggregation-free gold nanoparticles using poly(styrene-block-cysteine) [J].

Abraham, Sinoj ;

Kim, Il ;

Batt, Carl A. .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2007, 46 (30) :5720-5723

[3] Synthesis of stable "gold nanoparticle-polymeric micelle" conjugates: A new class of star "molecular chimera" that self-assemble into linear arrays of spherical micelles [J].

Abraham, Sinoj ;

Ha, Chang-Sik ;

Batt, Carl A. ;

Kim, Il .

JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 2007, 45 (16) :3570-3579

[4] Microfluidics assisted synthesis of well-defined spherical polymeric microcapsules and their utilization as potential encapsulants [J].

Abraham, Sinoj ;

Jeong, Eun Ho ;

Arakawa, Takahiro ;

Shoji, Shuichi ;

Kim, Kyung Chun ;

Kim, Il ;

Go, Jeung Sang .

LAB ON A CHIP, 2006, 6 (06) :752-756

[5] Design of environment-sensitive supramolecular assemblies for intracellular drug delivery: Polymeric micelles that are responsive to intracellular pH change [J].

Bae, Y ;

Fukushima, S ;

Harada, A ;

Kataoka, K .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2003, 42 (38) :4640-4643

[6] Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions [J].

Berkland, C ;

Kim, KK ;

Pack, DW .

JOURNAL OF CONTROLLED RELEASE, 2001, 73 (01) :59-74

[7] SEMIQUANTITATIVE METHOD FOR DETECTION OF MICROCAPSULE RESIDUES RESULTING FROM MICROENCAPSULATED PESTICIDE APPLICATIONS [J].

BLACKMER, GL ;

REYNOLDS, RH .

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1977, 25 (03) :559-561

[8] Formation of microcapsules from polyelectrolyte and covalent interactions [J].

Breguet, W ;

Gugerli, R ;

Pernetti, M ;

von Stockar, U ;

Marison, IW .

LANGMUIR, 2005, 21 (21) :9764-9772

[9] Polypeptide end-capping using functionalized isocyanates: Preparation of pentablock copolymers [J].

Brzezinska, KR ;

Curtin, SA ;

Deming, TJ .

MACROMOLECULES, 2002, 35 (08) :2970-2976

[10] Synthesis of ABA triblock copolymers via acyclic diene metathesis polymerization and living polymerization of α-amino acid-N-carboxyanhydrides [J].

Brzezinska, KR ;

Deming, TJ .

MACROMOLECULES, 2001, 34 (13) :4348-4354

← 1 2 3 4 5 6 7 8 →