Antigen adsorbed calcium phosphate nanoparticles stimulate both innate and adaptive immune response in fish, Labeo rohita H.

被引:23
作者
Behera, Truptimayee [1 ]
Swain, Priyabrat [1 ]
机构
[1] Cent Inst Freshwater Aquaculture, Fish Hlth Management Div, Bhubaneswar 751002, Orissa, India
关键词
Antigen; Adjuvant; Adaptive immunity; Aeromonas hydrophila; Calcium phosphate; Fish; Innate immunity; Nanoparticle; Parenteral immunization; S-layer protein; CYPRINUS-CARPIO L; AEROMONAS-HYDROPHILA; IMMUNOLOGICAL ADJUVANTS; CAMPYLOBACTER-FETUS; ALUMINUM-HYDROXIDE; PROTEINS; HYDROXYAPATITE; PROTECTION; MICROPARTICLES; TRANSFECTION;
D O I
10.1016/j.cellimm.2011.07.015
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Calcium phosphate nanoparticles as an antigen/protein delivery was explored in a fish model Labeo rohita H. S-layer protein (of Aeromonas hydrophila) adsorbed on nano sized calcium phosphate particles elicited both innate and adaptive immune parameters which persisted up to 63 days of post immunization through parenteral immunization and gave cross protections. (C) 2011 Elsevier Inc. All rights reserved.
引用
收藏
页码:350 / 359
页数:10
相关论文
共 61 条
  • [41] Humoral immune parameters in Atlantic cod (Gadus morhua L.) -: I.: The effects of environmental temperature
    Magnadóttir, B
    Jónsdóttir, H
    Helgason, S
    Björnsson, B
    Jorgensen, TO
    Pilström, L
    [J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 1999, 122 (02): : 173 - 180
  • [42] ROLE OF SURFACE COMPONENTS IN SERUM RESISTANCE OF VIRULENT AEROMONAS-SALMONICIDA
    MUNN, CB
    ISHIGURO, EE
    KAY, WW
    TRUST, TJ
    [J]. INFECTION AND IMMUNITY, 1982, 36 (03) : 1069 - 1075
  • [43] A comparative immunopathological study of injection site reactions in salmonids following intraperitoneal injection with oil-adjuvanted vaccines
    Mutoloki, S
    Reite, OB
    Brudeseth, B
    Tverdal, A
    Evensen, O
    [J]. VACCINE, 2006, 24 (05) : 578 - 588
  • [44] The use of size-defined DNA-functionalized calcium phosphate nanoparticles to minimise intracellular calcium disturbance during transfection
    Neumann, Sebastian
    Kovtun, Anna
    Dietzel, Irmgard D.
    Epple, Matthias
    Heumann, Rolf
    [J]. BIOMATERIALS, 2009, 30 (35) : 6794 - 6802
  • [45] Synthetic peptides entrapped in microparticles can elicit cytotoxic T cell activity
    Nixon, DF
    Hioe, C
    Chen, PD
    Bian, ZN
    Kuebler, P
    Li, ML
    Qiu, H
    Li, XM
    Singh, M
    Richardson, J
    McGee, P
    Zamb, T
    Koff, W
    Wang, CY
    OHagan, D
    [J]. VACCINE, 1996, 14 (16) : 1523 - 1530
  • [46] PHIPPS BM, 1988, J BIOL CHEM, V263, P9298
  • [47] Potter A. A., 2001, Current Drug Targets - Infectious Disorders, V1, P249, DOI 10.2174/1568005014606035
  • [48] A rapid, direct assay to measure degranulation of bovine neutrophil primary granules
    Quade, MJ
    Roth, JA
    [J]. VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 1997, 58 (3-4) : 239 - 248
  • [49] Outer membrane proteins of Aeromonas hydrophila induce protective immunity in goldfish
    Rahman, MH
    Kawai, K
    [J]. FISH & SHELLFISH IMMUNOLOGY, 2000, 10 (04) : 379 - 382
  • [50] Relyveld E H, 1986, Dev Biol Stand, V65, P131