What else has to happen for nitric oxide to induce cell death?

被引:18
作者
Borutaite, V [1 ]
Brown, G [1 ]
机构
[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England
关键词
apoptosis; hypoxia; necrosis; nitric oxide (NO); reactive oxygen species (ROS); superoxide production;
D O I
10.1042/BST0331394
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Nitric oxide (NO) can induce cell death; however, No-induced cell death may be dependent/conditional on factors other than NO itself. Whether No kills a particular cell depends on the amount of NO, source of NO, time of exposure to NO, cell type and the levels of other factors including, particularly oxygen, superoxide, H2O2, antioxiclants, thiols and glycolysis.
引用
收藏
页码:1394 / 1396
页数:3
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