Fine mapping of five human skeletal muscle genes: Alpha-tropomyosin, beta-tropomyosin, troponin-I slow-twitch, troponin-I fast-twitch, and troponin-c fast

被引：35

作者：

Tiso, N

Rampoldi, L

Pallavicini, A

Zimbello, R

Pandolfo, D

Valle, G

Lanfranchi, G

Danieli, GA

机构：

[1] UNIV PADUA,DEPT BIOL,I-35121 PADUA,ITALY

[2] UNIV PADUA,CRIBI,CTR BIOTECHNOL,I-35121 PADUA,ITALY

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1997年 / 230卷 / 02期

关键词：

D O I：

10.1006/bbrc.1996.5958

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper the chromosomal localization of the human skeletal muscle genes Troponin-I slow-twitch (TNNI1), Troponin-I fast-twitch (TNNI2), and Troponin-C fast (TNNC2) and the refinement of the position for alpha-Tropomyosin (TPM1) and beta-Tropomyosin (TPM2) are reported. By radiation hybrid mapping, TPM1 was assigned to chromosome 15q22.1, TPM2 to chromosome 9p13.2-p13.1, TNNI1 to chromosome 1q31.3, TNNI2 to chromosome 11p15.5, and TNNC2 to chromosome 20q12-q13.11. The genomic distribution of these genes is discussed, with particular emphasis on the cluster organization of the Troponin genes. (C) 1997 Academic Press

引用

页码：347 / 350

页数：4

共 22 条

[1]

BAMSHAD M, 1994, AM J HUM GENET, V55, P1153

[2] Mapping TNNC1, the gene that encodes cardiac troponin I in the human and the mouse [J].

Bermingham, N ;

Hernandez, D ;

Balfour, A ;

Gilmour, F ;

Martin, JE ;

Fisher, EMC .

GENOMICS, 1995, 30 (03) :620-622

[3] RADIATION HYBRID MAPPING - A SOMATIC-CELL GENETIC METHOD FOR CONSTRUCTING HIGH-RESOLUTION MAPS OF MAMMALIAN CHROMOSOMES [J].

COX, DR ;

BURMEISTER, M ;

PRICE, ER ;

KIM, S ;

MYERS, RM .

SCIENCE, 1990, 250 (4978) :245-250

[4] ASSIGNMENT OF THE HUMAN SKELETAL-MUSCLE ALPHA-TROPOMYOSIN GENE (TPM1) TO BAND 15Q22 BY FLUORESCENCE IN-SITU HYBRIDIZATION [J].

EYRE, H ;

AKKARI, PA ;

WILTON, SD ;

CALLEN, DC ;

BAKER, E ;

LAING, NG .

CYTOGENETICS AND CELL GENETICS, 1995, 69 (1-2) :15-17

[5] Cardiac and skeletal muscle troponin I isoforms are encoded by a dispersed gene family on mouse Chromosomes 1 and 7 [J].

Guenet, JL ;

SimonChazottes, D ;

Gravel, M ;

Hastings, KEM ;

Schiaffino, S .

MAMMALIAN GENOME, 1996, 7 (01) :13-15

[6] A SURVEY ON INTRON AND EXON LENGTHS [J].

HAWKINS, JD .

NUCLEIC ACIDS RESEARCH, 1988, 16 (21) :9893-9908

[7] AN STS-BASED MAP OF THE HUMAN GENOME [J].

HUDSON, TJ ;

STEIN, LD ;

GERETY, SS ;

MA, JL ;

CASTLE, AB ;

SILVA, J ;

SLONIM, DK ;

BAPTISTA, R ;

KRUGLYAK, L ;

XU, SH ;

HU, XT ;

COLBERT, AME ;

ROSENBERG, C ;

REEVEDALY, MP ;

ROZEN, S ;

HUI, L ;

WU, XY ;

VESTERGAARD, C ;

WILSON, KM ;

BAE, JS ;

MAITRA, S ;

GANIATSAS, S ;

EVANS, CA ;

DEANGELIS, MM ;

INGALLS, KA ;

NAHF, RW ;

HORTON, LT ;

ANDERSON, MO ;

COLLYMORE, AJ ;

YE, WJ ;

KOUYOUMJIAN, V ;

ZEMSTEVA, IS ;

TAM, J ;

DEVINE, R ;

COURTNEY, DF ;

RENAUD, MT ;

NGUYEN, H ;

OCONNOR, TJ ;

FIZAMES, C ;

FAURE, S ;

GYAPAY, G ;

DIB, C ;

MORISSETTE, J ;

ORLIN, JB ;

BIRREN, BW ;

GOODMAN, N ;

WEISSENBACH, J ;

HAWKINS, TL ;

FOOTE, S ;

PAGE, DC .

SCIENCE, 1995, 270 (5244) :1945-1954

[8] ASSIGNMENT OF THE HUMAN BETA-TROPOMYOSIN GENE (TPM2) TO BAND 9P13 BY FLUORESCENCE IN-SITU HYBRIDIZATION [J].

HUNT, CCJ ;

EYRE, HJ ;

AKKARI, PA ;

MEREDITH, C ;

DOROSZ, SM ;

WILTON, SD ;

CALLEN, DF ;

LAING, NG ;

BAKER, E .

CYTOGENETICS AND CELL GENETICS, 1995, 71 (01) :94-95

[9] Identification of 4370 expressed sequence tags from a 3'-end-specific cDNA library of human skeletal muscle by DNA sequencing and filter hybridization [J].

Lanfranchi, G ;

Muraro, T ;

Caldara, F ;

Pacchioni, B ;

Pallavicini, A ;

Pandolfo, D ;

Toppo, S ;

Trevisan, S ;

Scarso, S ;

Valle, G .

GENOME RESEARCH, 1996, 6 (01) :35-42

[10] THE HUMAN CARDIAC TROPONIN-I LOCUS - ASSIGNMENT TO CHROMOSOME 19P13.2-19Q13.2 [J].

MACGEOCH, C ;

BARTON, PJR ;

VALLINS, WJ ;

BHAVSAR, P ;

SPURR, NK .

HUMAN GENETICS, 1991, 88 (01) :101-104

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