Monstrous attempts at adnexogenesis: regulating hair follicle progenitors through Sonic hedgehog signaling

被引：60

作者：

Callahan, CA ^{[1
]}

Oro, AE ^{[1
]}

机构：

[1] Stanford Univ, Program Epithelial Biol, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(00)00230-6

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Epithelial organs such as the vertebrate hair control periodic self-renewal by regulating the growth of progenitor cells. Recent studies implicate Sonic hedgehog target gene induction in the growth of multipotent hair follicle epithelium and the development of a variety of hair follicle tumors such as basal cell carcinomas. These studies suggest Sonic hedgehog signaling may regulate progenitor cells in other organs.

引用

页码：541 / 546

页数：6

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