A transcriptome analysis of Kluyveromyces lactic growing in cheese whey

被引：8

作者：

Becerra, M ^{[1
]}

González-Siso, MI ^{[1
]}

Cerdán, ME ^{[1
]}

机构：

[1] Univ A Coruna, Dept Biol Celular & Mol, F Ciencias, La Coruna 15071, Spain

来源：

INTERNATIONAL DAIRY JOURNAL | 2006年 / 16卷 / 03期

关键词：

Kluyveromyces lactis; cheese whey; transcriptome; DNA array; secretion;

D O I：

10.1016/j.idairyj.2005.03.005

中图分类号：

TS2 [食品工业];

学科分类号：

0832 [食品科学与工程];

摘要：

Heterologous DNA-arrays from Saccharomyces cerevisiae were used to study the changes of the Kluyveromyces lactis transcriptome when this yeast was grown in cheese whey (CW) rather than in synthetic media. The results revealed a complete rearrangement in the expression of genes related to glycosylation and secretion pathways when the growth medium was changed. The yeast system was also used to test the advantages of whey supplements as antioxidant protectors. Growth of K lactic in CW did not cause an increase in transcription of genes related to glutathione biosynthesis. However, other genes, related to glutathione metabolism and the oxidative stress response, were over expressed in this medium. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：207 / 214

页数：8

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