Human metapneumovirus-associated lower respiratory tract infections in Korean infants and young children

被引：19

作者：

Kim, YK

Lee, HJ

机构：

[1] Korea Univ, Coll Med, Dept Pediat, Seoul, South Korea

[2] Seoul Natl Univ, Coll Med, Dept Pediat, Seoul, South Korea

[3] Seoul Natl Univ Hosp, Virus Res Ctr, Clin Res Inst, Seoul 110744, South Korea

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2005年 / 24卷 / 12期

关键词：

human metapneumovirus; lower respiratory tract infection; pneumonia; bronchiolitis;

D O I：

10.1097/01.inf.0000190042.65120.23

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To define the role of human metapneumovirus (hMPV) in previously healthy Korean children, a retrospective study was done on 166 children with lower respiratory tract infections and oil their stored nasal aspirates. The hMPV gene was detected by reverse transcriptase-polymerase chain reaction. Twenty-six of 166 individuals tested positive for hMPV. The clinical diagnoses of hMPV infection were pneumonia in 15 children and bronchiolitis in 11 children.

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页码：1111 / 1112

页数：2

相关论文

共 15 条

[1]

Boivin G, 2003, EMERG INFECT DIS, V9, P634

[2] Genetic diversity and molecular epidemiology of the G protein of subgroups A and B of respiratory syncytial viruses isolated over 9 consecutive epidemics in Korea [J].

Choi, EH ;

Lee, HJ .

JOURNAL OF INFECTIOUS DISEASES, 2000, 181 (05) :1547-1556

[3] Diagnosis of respiratory syncytial virus infection: Comparison of reverse transcription-PCR to viral culture and serology in adults with respiratory illness [J].

Falsey, AR ;

Formica, MA ;

Walsh, EE .

JOURNAL OF CLINICAL MICROBIOLOGY, 2002, 40 (03) :817-820

[4] Human metapneumovirus infections in young and elderly adults [J].

Falsey, AR ;

Erdman, D ;

Anderson, LJ ;

Walsh, EE .

JOURNAL OF INFECTIOUS DISEASES, 2003, 187 (05) :785-790

[5] Presence of the new human metapneumovirus in French children with bronchiolitis [J].

Freymuth, F ;

Vabret, A ;

Legrand, L ;

Eterradossi, N ;

Lafay-Delaire, F ;

Brouard, J ;

Guillois, B .

PEDIATRIC INFECTIOUS DISEASE JOURNAL, 2003, 22 (01) :92-94

[6] Lower respiratory tract infections due to adenovirus in hospitalized Korean children: Epidemiology, clinical features, and prognosis [J].

Hong, JY ;

Lee, HJ ;

Piedra, PA ;

Choi, EH ;

Park, KH ;

Koh, YY ;

Kim, WS .

CLINICAL INFECTIOUS DISEASES, 2001, 32 (10) :1423-1429

[7] Simultaneous detection, subgrouping, and quantitation of respiratory syncytial virus A and B by real-time PCR [J].

Hu, AZ ;

Colella, M ;

Tam, JS ;

Rappaport, R ;

Cheng, SM .

JOURNAL OF CLINICAL MICROBIOLOGY, 2003, 41 (01) :149-154

[8] Metapneumovirus and acute wheezing in children [J].

Jartti, T ;

van den Hoogen, B ;

Garofalo, RP ;

Osterhaus, ADME ;

Ruuskanen, O .

LANCET, 2002, 360 (9343) :1393-1394

[9] Evaluation of the Hexaplex assay for detection of respiratory viruses in children [J].

Kehl, SC ;

Henrickson, KJ ;

Hua, WM ;

Fan, J .

JOURNAL OF CLINICAL MICROBIOLOGY, 2001, 39 (05) :1696-1701

[10] Evidence of human metapneumovirus in Australian children [J].

Nissen, MD ;

Siebert, DJ ;

Mackay, IM ;

Sloots, TP ;

Withers, SJ .

MEDICAL JOURNAL OF AUSTRALIA, 2002, 176 (04) :188-188