Relationship between ciprofloxacin resistance and extended-spectrum β-lactamase production in Escherichia coli and Klebsiella pneumoniae strains

被引:51
作者
Tolun, V
Küçükbasmaci, Ö
Törümküney-Akbulut, D
Çatal, Ç
Ang-Küçüker, M [1 ]
Ang, Ö
机构
[1] Univ Istanbul, Fac Med, Dept Microbiol & Clin Microbiol, TR-34390 Istanbul, Turkey
[2] Univ Istanbul, Expt Med Res Inst, TR-34390 Istanbul, Turkey
关键词
beta-Lactamase; ciprofloxacin; Escherichia coli; extended-spectrum beta-lactamases; Klebsiella pneumoniae; resistance;
D O I
10.1111/j.1469-0691.2004.00723.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Resistance to fluoroquinolones has increased markedly since their introduction. Mechanisms of resistance to any antibiotic class might play a role in resistance to an unrelated antibiotic class. This study evaluated the relationship between extended-spectrum beta-lactamase (ESBL) production and ciprofloxacin resistance in Escherichia coli and Klebsiella pneumoniae strains isolated as causative agents of urinary tract infection. ESBL-producing strains were significantly more frequent among ciprofloxacin-resistant E. coli strains than among ciprofloxacin-susceptible E. coli strains (p = 0.015), but the difference was not significant among K. pneumoniae strains (p = 0.276).
引用
收藏
页码:72 / 75
页数:4
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