Highly satisfactory procedures for the Pd-catalyzed cross coupling of aryl electrophiles with in situ generated alkynylzinc derivatives

被引：101

作者：

Anastasia, L ^{[1
]}

Negishi, E ^{[1
]}

机构：

[1] Purdue Univ, Herbert C Brown Lab Chem, W Lafayette, IN 47907 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 20期

关键词：

D O I：

10.1021/ol010145q

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Two new and very efficient procedures (Procedures A and B) are reported for the Pd-catalyzed cross coupling of aryl electrophiles; with terminal alkynes via their in situ conversion into alkynylzinc derivatives. Procedure A is particularly valuable in cases where electron-deficient alkynes are used, while Procedure B is operationally simple and very satisfactory in less demanding cases.

引用

页码：3111 / 3113

页数：3

共 41 条

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