Phenylnaphthalene compounds from the subterranean part of Vitex rotundifolia and their antibacterial activity against methicillin-resistant Staphylococcus aureus

被引:67
作者
Kawazoe, K [1 ]
Yutani, A [1 ]
Tamemoto, K [1 ]
Yuasa, S [1 ]
Shibata, H [1 ]
Higuti, T [1 ]
Takaishi, Y [1 ]
机构
[1] Univ Tokushima, Fac Pharmaceut Sci, Tokushima 7708505, Japan
来源
JOURNAL OF NATURAL PRODUCTS | 2001年 / 64卷 / 05期
关键词
D O I
10.1021/np000307b
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
A careful investigation of the subterranean part of Vitex rotundifolia has shown that this plant contains five novel lignans having a 1-phenylnaphthalene-type skeleton together with four known lignans. These structures were elucidated on the basis of spectroscopic data. Furthermore, some of the isolated compounds showed antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
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页码:588 / 591
页数:4
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