Proteomics from the clinical perspective: many hopes and much debate

被引：61

作者：

Beretta, Laura ^{[1
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Mol Diagnost Program, Seattle, WA 98109 USA

来源：

NATURE METHODS | 2007年 / 4卷 / 10期

关键词：

D O I：

10.1038/nmeth1007-785

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Mass spectrometry has been rapidly maturing as the core technology at the heart of proteomics. The application of these powerful methods to the study of human diseases and their translation to the clinic, however, has been beset with unique challenges.

引用

页码：785 / 786

页数：2

共 19 条

[11] Proteomics-based development of biomarkers in cardiovascular disease - Mechanistic, clinical, and therapeutic insights [J].

Mayr, Manuel ;

Zhang, Jun ;

Greene, Andrew S. ;

Gutterman, David ;

Perloff, Joseph ;

Ping, Peipei .

MOLECULAR & CELLULAR PROTEOMICS, 2006, 5 (10) :1853-1864

[12] Clinical proteomics: A need to define the field and to begin to set adequate standards [J].

Mischak, Harald ;

Apweiler, Rolf ;

Banks, Rosamonde E. ;

Conaway, Mark ;

Coon, Joshua ;

Dominiczak, Anna ;

Ehrich, Jochen H. H. ;

Fliser, Danilo ;

Girolami, Mark ;

Hermjakob, Henning ;

Hochstrasser, Denis ;

Jankowski, Joachim ;

Julian, Bruce A. ;

Kolch, Walter ;

Massy, Ziad A. ;

Neusuess, Christian ;

Novak, Jan ;

Peter, Karlheinz ;

Rossing, Kasper ;

Schanstra, Joost ;

Semmes, O. John ;

Theodorescu, Dan ;

Thongboonkerd, Visith ;

Weissinger, Eva M. ;

Van Eyk, Jennifer E. ;

Yamamoto, Tadashi .

PROTEOMICS CLINICAL APPLICATIONS, 2007, 1 (02) :148-156

[13] Clinical proteomics: Revolutionizing disease detection and patient tailoring therapy [J].

Petricoin, E ;

Wulfkuhle, J ;

Espina, V ;

Liotta, LA .

JOURNAL OF PROTEOME RESEARCH, 2004, 3 (02) :209-217

[14]

PRAKASH A, 2007, MOL CELL PROTEOMICS

[15] Clinical proteomics and mass spectrometry profiling for cancer detection [J].

Solassol, Jerome ;

Jacot, William ;

Lhermitte, Ludovic ;

Boulle, Nathalie ;

Maudelonde, Thierry ;

Mange, Alain .

EXPERT REVIEW OF PROTEOMICS, 2006, 3 (03) :311-320

[16] The work of the Human Proteome Organisation's Proteomics Standards Initiative (HUPO PSI) [J].

Taylor, Chris F. ;

Hermjakob, Henning ;

Julian, Randall K., Jr. ;

Garavelli, John S. ;

Aebersold, Ruedi ;

Apweiler, Rolf .

OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY, 2006, 10 (02) :145-151

[17] Mass spectrometry: Uncovering the cancer proteome for diagnostics [J].

van der Merwe, Da-Elene ;

Oikonomopoulou, Katerina ;

Marshall, John ;

Diamandis, Eleftherios P. .

ADVANCES IN CANCER RESEARCH, VOL 96, 2007, 96 :23-50

[18] Global and targeted quantitative proteomics for biomarker discovery [J].

Veenstra, Timothy D. .

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2007, 847 (01) :3-11

[19] Mass spectrometric detection of tissue proteins in plasma [J].

Zhang, Hui ;

Liu, Alvin Y. ;

Loriaux, Paul ;

Wollscheid, Bernd ;

Zhou, Yong ;

Watts, Julian D. ;

Aebersold, Ruedi .

MOLECULAR & CELLULAR PROTEOMICS, 2007, 6 (01) :64-71

← 1 2 →