LOCALLY WEIGHTED MARKOV RANDOM FIELDS FOR CORTICAL SEGMENTATION

被引:3
作者
Cardoso, Manuel Jorge [1 ]
Clarkson, Matthew J. [1 ]
Modat, Marc [1 ]
Ridgway, Gerard R. [1 ]
Ourselin, Sebastien [1 ]
机构
[1] UCL, Ctr Med Image Comp, London, England
来源
2010 7TH IEEE INTERNATIONAL SYMPOSIUM ON BIOMEDICAL IMAGING: FROM NANO TO MACRO | 2010年
关键词
Markov random field; Expectation-Maximisation; cortical segmentation; partial volume effect; MR-IMAGES; MODEL;
D O I
10.1109/ISBI.2010.5490146
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Segmenting the human brain from magnetic resonance images is a challenging task due to the convoluted shape of the cortex, noise, intensity non-uniformity and partial volume effects. We propose a new way to overcome part of the bias-variance tradeoff existent in any segmentation technique by locally varying the behaviour of the model. We developed a novel metric based on the Laplacian of the geodesic distance to localise and iteratively modify the prior information and Markov random field weights, leading to a better delineation of deep sulci and narrow gyri. Experiments performed on 20 Brainweb datasets show statistically significant improvements in Dice scores and partial volume estimation when compared to two well established techniques.
引用
收藏
页码:956 / 959
页数:4
相关论文
共 10 条
[1]  
Acosta O, 2008, LECT NOTES COMPUT SC, V5241, P253, DOI 10.1007/978-3-540-85988-8_31
[2]   Unified segmentation [J].
Ashburner, J ;
Friston, KJ .
NEUROIMAGE, 2005, 26 (03) :839-851
[3]  
CARDOSO MJ, 2009, LECT NOTES COMPUTER, P441
[4]   Different regional patterns of cortical thinning in Alzheimer's disease and frontotemporal dementia [J].
Du, An-Tao ;
Schuff, Norbert ;
Kramer, Joel H. ;
Rosen, Howard J. ;
Gorno-Tempini, Maria Luisa ;
Rankin, Katherine ;
Miller, Bruce L. ;
Weiner, Michael W. .
BRAIN, 2007, 130 :1159-1166
[5]   Voxel-based cortical thickness measurements in MRI [J].
Hutton, Chloe ;
De Vita, Enrico ;
Ashburner, John ;
Deichmann, Ralf ;
Turner, Robert .
NEUROIMAGE, 2008, 40 (04) :1701-1710
[6]   Evaluation of Automated Brain MR Image Segmentation and Volumetry Methods [J].
Klauschen, Frederick ;
Goldman, Aaron ;
Barra, Vincent ;
Meyer-Lindenberg, Andreas ;
Lundervold, Arvid .
HUMAN BRAIN MAPPING, 2009, 30 (04) :1310-1327
[7]   Thinning of the cerebral cortex in aging [J].
Salat, DH ;
Buckner, RL ;
Snyder, AZ ;
Greve, DN ;
Desikan, RSR ;
Busa, E ;
Morris, JC ;
Dale, AM ;
Fischl, B .
CEREBRAL CORTEX, 2004, 14 (07) :721-730
[8]  
SHEFER V F, 1973, Neuroscience and Behavioral Physiology, V6, P319, DOI 10.1007/BF01182672
[9]   Automated model-based tissue classification of MR images of the brain [J].
Van Leemput, K ;
Maes, F ;
Vandermeulen, D ;
Suetens, P .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 1999, 18 (10) :897-908
[10]   Segmentation of brain MR images through a hidden Markov random field model and the expectation-maximization algorithm [J].
Zhang, YY ;
Brady, M ;
Smith, S .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2001, 20 (01) :45-57