Dioxin may promote inflammation-related development of endometriosis

被引:47
作者
Bruner-Tran, Kaylon L. [1 ]
Yeaman, Grant R. [1 ]
Crispens, Marta A. [1 ]
Igarashi, Toshio M. [1 ]
Osteen, Kevin G. [1 ]
机构
[1] Vanderbilt Univ, Sch Med, Womens Reprod Hlth Res Ctr, Dept Obstet & Gynecol, Nashville, TN 37232 USA
关键词
endometriosis; dioxin; progesterone; inflammation; leukocytes;
D O I
10.1016/j.fertnstert.2008.02.102
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Laboratory and population-based studies suggest that exposure to environmental toxicants may be one of several triggers for the development of endometriosis. We discuss evidence that modulation of the endometrial endocrine-immune interface could mechanistically link toxicant exposure to the development of this disease.
引用
收藏
页码:1287 / 1298
页数:12
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