Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

被引：243

作者：

Collier, RJ ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Microbiol & Mol Genet, Boston, MA 02115 USA

来源：

TOXICON | 2001年 / 39卷 / 11期

关键词：

toxin; ADP-Ribosylation; translocation; receptor;

D O I：

10.1016/S0041-0101(01)00165-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Diphtheria toxin is one of the most extensively studied and well understood bacterial toxins. Ever since its discovery in the late 1800's this toxin has occupied a central focus in the field of toxinology. In this review, I present a chronology of major discoveries that led to our current understanding of the structure and activity of diphtheria toxin. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1793 / 1803

页数：11

共 113 条

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