Arousal and inhibition of human NK cells

被引:215
作者
Lanier, LL
Corliss, B
Phillips, JH
机构
[1] DNAX Research Institute, Palo Alto, CA 94304
关键词
D O I
10.1111/j.1600-065X.1997.tb00947.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
NK cells express receptors for polymorphic MHC class I molecules that inhibit killing of potential target cells bearing appropriate class I allotypes. Here we review the membrane receptors on human NK cells that are known to initiate cell-mediated cytotoxicity and demonstrate regula tion of these responses by the killer cell inhibitory (KIR) receptors.
引用
收藏
页码:145 / 154
页数:10
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