Dopamine transporter imaging study in parkinsonism occurring in fragile X premutation carriers

被引：23

作者：

Ceravolo, R

Antonini, A

Volterrani, D

Rossi, C

Goldwurm, S

Di Maria, E

Kiferle, L

Bonuccelli, U

Murri, L

机构：

[1] Univ Pisa, Neurol Sect, Dept Neurosci, I-56126 Pisa, Italy

[2] Ist Clin Perfezionamento, Parkinson Inst, Milan, Italy

[3] Univ Pisa, Ctr Nucl Med, I-56100 Pisa, Italy

[4] Univ Genoa, Med Genet Sect, Dept Neurosci Ophthalmol & Genet, Genoa, Italy

来源：

NEUROLOGY | 2005年 / 65卷 / 12期

关键词：

D O I：

10.1212/01.wnl.0000188821.51055.52

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors studied four patients with parkinsonism carrying the fragile X premutation using SPECT with [I-23]FP-CIT. They found evidence of preserved presynaptic nigrostriatal function, suggesting that parkinsonism in the X fragile premutation might be related to postsynaptic dopaminergic changes or different neurotransmitter alterations.

引用

页码：1971 / 1973

页数：3

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