Enantioselective permeation of racemates through a solid (+)-poly{2-[dimethyl(10-pinanyl)silyl]norbornadiene} membrane

被引：43

作者：

Aoki, T

Ohshima, M

Shinohara, KI

Kaneko, T

Oikawa, E

机构：

[1] Grad. Sch. of Science and Technology, Niigata University, Niigata 950-21

来源：

POLYMER | 1997年 / 38卷 / 01期

关键词：

pinanyl group; optical resolution membrane; propranolol;

D O I：

10.1016/S0032-3861(96)00630-1

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A novel norbornadiene polymer having optically active pinanyl groups in the pendant groups was synthesized as an optical resolution membrane material. The resulting polymer membrane showed highly enantioselective permeability for racemic propranolol used as a medicine. The permeability of tryptophan was much higher than that of a (+)-poly{1-[dimethyl(10-pinanyl)silyl]-1-propyne} membrane we reported previously. Copyright (C) 1996 Elsevier Science Ltd.

引用

页码：235 / 238

页数：4

共 11 条

[1]

AOKI T, 1992, MAKROMOL CHEM-RAPID, V13, P565

[2] OPTICAL RESOLUTION BY USE OF SURFACE-MODIFIED POLY(METHYL METHACRYLATE) MEMBRANE CONTAINING(-)-OLIGO(METHYL(10-PINANYL)SILOXANE) [J].