Electro-chemiluminescent biosensing

被引:150
作者
Marquette, Christophe A. [1 ]
Blum, Loiec J. [1 ]
机构
[1] Univ Lyon 1, CNRS, Inst Chim & Biochim Mol & Supramol, ICBMS,Lab Gen Enzymat & Biomol, F-69622 Villeurbanne, France
关键词
biochip; biosensor; DNA; electro-chemiluminescence; enzyme; immunochemical;
D O I
10.1007/s00216-007-1631-2
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The present review draws a general picture of the bioanalytical applications of electro-chemiluminescent reactions (ECL). Only the two main ECL reactions-i.e. the luminol-based and Ru(bpy)(3)(2+)-based reactions-are considered for application in the fields of enzyme biosensors, immunochemical biosensors, DNA biosensors, and biochips. The mechanism, principle, and experimental conditions of these two reactions are described. Then, for each category of analytical tools, experimental set-ups and performances are presented and discussed.
引用
收藏
页码:155 / 168
页数:14
相关论文
共 77 条
[1]  
[Anonymous], 1978, METHODS ENZYMOL, DOI DOI 10.1016/0076-6879(78)57038-9
[2]  
ARCAMONE F, 1983, DOXORUBIEIN ANTICANC
[3]   Sub-microliter electrochemiluminescence detector - A model for small volume analysis systems [J].
Arora, A ;
de Mello, AJ ;
Manz, A .
ANALYTICAL COMMUNICATIONS, 1997, 34 (12) :393-395
[4]  
Bard A.J., 2004, ELECTROGENERATED CHE
[5]   ELECTROGENERATED CHEMI-LUMINESCENCE FROM 9,10-DIPHENYLANTHRACENE CATIONS REACTING WITH RADICAL-ANIONS [J].
BEIDEMAN, FE ;
HERCULES, DM .
JOURNAL OF PHYSICAL CHEMISTRY, 1979, 83 (17) :2203-2209
[6]  
BLACKBURN GF, 1991, CLIN CHEM, V37, P1534
[7]   CHEMILUMINESCENT FLOW-INJECTION ANALYSIS OF GLUCOSE IN DRINKS WITH A BIENZYME FIBEROPTIC BIOSENSOR [J].
BLUM, LJ .
ENZYME AND MICROBIAL TECHNOLOGY, 1993, 15 (05) :407-411
[8]  
BLUM LJ, 1997, BIO CHEMI LUMINESCEN
[9]   Detection of DNA hybridization by ABEI electrochemiluminescence in DNA-chip compatible assembly [J].
Calvo-Muñoz, ML ;
Dupont-Filliard, A ;
Billon, M ;
Guillerez, S ;
Bidan, G ;
Marquette, C ;
Blum, L .
BIOELECTROCHEMISTRY, 2005, 66 (1-2) :139-143
[10]   Micropatterns of protein and conducting polymer molecules fabricated by layer-by-layer self-assembly and photolithography techniques [J].
Cao, TB ;
Wei, F ;
Jiao, XM ;
Chen, JY ;
Liao, W ;
Zhao, X ;
Cao, WX .
LANGMUIR, 2003, 19 (20) :8127-8129