Angiotensin II type 2 receptors: signalling and pathophysiological role

被引：20

作者：

Blume, A ^{[1
]}

Kaschina, E ^{[1
]}

Unger, T ^{[1
]}

机构：

[1] Univ Kiel, Inst Pharmacol, D-24105 Kiel, Germany

来源：

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION | 2001年 / 10卷 / 02期

关键词：

D O I：

10.1097/00041552-200103000-00013

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

The signalling mechanisms and biological significance of the angiotensin II type 2 receptor have long been unknown. In recent years, studies, first in cell culture models but now increasingly also in vivo, have shed some light on the molecular events occurring after a stimulation of the receptor with its ligand as well as on its physiological effects and its significance for pathophysiological processes. There is increasing evidence that the angiotensin II type 2 receptor is involved in different pathophysiological processes, such as myocardial infarction, heart and kidney failure, and stroke. Curr Opin Nephrol Hypertens 10:239-246. (C) 2001 Lippincott Williams & Wilkins.

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页码：239 / 246

页数：8

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