The UCSC Genome Browser database: update 2011

被引：761

作者：

Fujita, Pauline A. ^{[1
]}

Rhead, Brooke ^{[1
]}

Zweig, Ann S. ^{[1
]}

Hinrichs, Angie S. ^{[1
]}

Karolchik, Donna ^{[1
]}

Cline, Melissa S. ^{[1
]}

Goldman, Mary ^{[1
]}

Barber, Galt P. ^{[1
]}

Clawson, Hiram ^{[1
]}

Coelho, Antonio ^{[1
]}

Diekhans, Mark ^{[1
]}

Dreszer, Timothy R. ^{[1
]}

Giardine, Belinda M. ^{[2
]}

Harte, Rachel A. ^{[1
]}

Hillman-Jackson, Jennifer ^{[1
]}

Hsu, Fan ^{[1
]}

Kirkup, Vanessa ^{[1
]}

Kuhn, Robert M. ^{[1
]}

Learned, Katrina ^{[1
]}

Li, Chin H. ^{[1
]}

Meyer, Laurence R. ^{[1
]}

Pohl, Andy ^{[1
,3
]}

Raney, Brian J. ^{[1
]}

Rosenbloom, Kate R. ^{[1
]}

Smith, Kayla E. ^{[1
]}

Haussler, David ^{[1
,4
]}

Kent, W. James ^{[1
]}

机构：

[1] Univ Calif Santa Cruz, Sch Engn, Ctr Biomol Sci & Engn, Santa Cruz, CA 95064 USA

[2] Penn State Univ, Huck Inst Life Sci, Ctr Comparat Genom & Bioinformat, University Pk, PA 16802 USA

[3] Ctr Genom Regulat CRG, Barcelona, Spain

[4] Univ Calif Santa Cruz, Howard Hughes Med Inst, Santa Cruz, CA 95064 USA

来源：

NUCLEIC ACIDS RESEARCH | 2011年 / 39卷

关键词：

SEQUENCE;

D O I：

10.1093/nar/gkq963

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The University of California, Santa Cruz Genome Browser (http://genome.ucsc.edu) offers online access to a database of genomic sequence and annotation data for a wide variety of organisms. The Browser also has many tools for visualizing, comparing and analyzing both publicly available and user-generated genomic data sets, aligning sequences and uploading user data. Among the features released this year are a gene search tool and annotation track drag-reorder functionality as well as support for BAM and BigWig/BigBed file formats. New display enhancements include overlay of multiple wiggle tracks through use of transparent coloring, options for displaying transformed wiggle data, a 'mean+whiskers' windowing function for display of wiggle data at high zoom levels, and more color schemes for microarray data. New data highlights include seven new genome assemblies, a Neandertal genome data portal, phenotype and disease association data, a human RNA editing track, and a zebrafish Conservation track. We also describe updates to existing tracks.

引用

页码：D876 / D882

页数：7

共 42 条

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[42] The ENCODE project at UC Santa Cruz [J].

Thomas, Daryl J. ;

Rosenbloom, Kate R. ;

Clawson, Hiram ;

Hinrichs, Angie S. ;

Trumbower, Heather ;

Raney, Brian J. ;

Karolchik, Donna ;

Barber, Galt P. ;

Harte, Rachel A. ;

Hillman-Jackson, Jennifer ;

Kuhn, Robert M. ;

Rhead, Brooke L. ;

Smith, Kayla E. ;

Thakkapallayil, Archana ;

Zweig, Ann S. ;

Haussler, David ;

Kent, W. James .

NUCLEIC ACIDS RESEARCH, 2007, 35 :D663-D667

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