Pulsatilla chinensis: A review of traditional uses, phytochemistry and pharmacology research progress

被引:15
作者
Zhao, Zefeng [1 ,2 ]
Nian, Meng [2 ]
Qiao, Haifa [1 ,2 ]
Li, Bin [3 ]
Zheng, Xiaohui [3 ]
机构
[1] Shaanxi Univ Chinese Med, Coll Acupuncture & Massage, Taiyuan 712046, Shanxi, Peoples R China
[2] Shaanxi Key Lab Acupuncture & Med, Taiyuan 712046, Shanxi, Peoples R China
[3] Northwest Univ, Key Lab Resource Biol & Biotechnol Western China, Biomed Key Lab Shaanxi Prov, Sch Pharm,Minist Educ, 229 Taibai Rd, Xian 710069, Peoples R China
基金
中国国家自然科学基金;
关键词
Pulsatilla chinensis; Triterpenoids; Antitumor; Review; BUNGE REGEL; TRITERPENOIDAL SAPONINS; HEMOLYTIC TOXICITY; CYTOTOXIC ACTIVITY; ANTITUMOR-ACTIVITY; MASS-SPECTROMETRY; ROOTS; ACID; DERIVATIVES; RAT;
D O I
10.1016/j.arabjc.2021.103403
中图分类号
O6 [化学];
学科分类号
070301 [无机化学];
摘要
This paper is intended to review advances in the botanical, traditional uses, phytochemical and pharmacological studies of the Pulsatilla chinensis. Up to date, 68 kinds of chemical constituents have been isolated and identified from P. chinensis. Among these compounds, triterpenoids, flavonoids, lignans and coumarins are the major constituents. Researches about the pharmacological properties of P. chinensis revealed that this plant exhibited therapeutic potential both in vivo and in vitro, including antitumor, anti-inflammatory, anti-microbial and antiviral activities. Further attention should be paid to gathering information about their toxicology data, quality-control measures, and the clinical value of the active compounds from P. chinensis. (C) 2021 The Authors. Published by Elsevier B.V.
引用
收藏
页数:15
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