Studies toward the total synthesis of popolohuanone E:: Enantioselective synthesis of 8-O-methylpopolohuanone E

被引：46

作者：

Katoh, T ^{[1
]}

Nakatani, M ^{[1
]}

Shikita, S ^{[1
]}

Sampe, R ^{[1
]}

Ishiwata, A ^{[1
]}

Ohmori, O ^{[1
]}

Nakamura, M ^{[1
]}

Terashima, S ^{[1
]}

机构：

[1] Sagami Chem Res Ctr, Sagamihara, Kanagawa 2290012, Japan

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 17期

关键词：

D O I：

10.1021/ol016285h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHIC] 8-O-Methylpopolohuanone E (2) was synthesized in a highly convergent manner starting from the cis-fused decalin derivative accessible from the (-)-Wieland-Miescher ketone analogue. The synthetic method features a biogenetic-type annulation of the phenolic and quinone segments to regioselectively construct the central tricyclic ring system as the key step.

引用

页码：2701 / 2704

页数：4