Synthetic analogues of the active sites of iron-sulfur proteins

被引：505

作者：

Rao, PV ^{[1
]}

Holm, RH ^{[1
]}

机构：

[1] Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA

来源：

CHEMICAL REVIEWS | 2004年 / 104卷 / 02期

关键词：

D O I：

10.1021/cr020615+

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Synthetic analogues of the active sites in iron-sulfur proteins were studied. X-ray crystallography was used to study the structures. Electron configurations, magnetic ground states and kinetic liability to substitution of terminal ligands were also studied. It was found that all the properties can be attributed to the weak-field nature of the complexes and the clusters.

引用

页码：527 / 559

页数：33

共 353 条

[21] IRON SULFUR DIMERS WITH BENZIMIDAZOLATE THIOLATE, BENZIMIDAZOLATE PHENOLATE, OR BIS(BENZIMIDAZOLATE) TERMINAL CHELATING LIGANDS [J].

BEARDWOOD, P ;

GIBSON, JF .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1986, (06) :490-492

[22] Iron-sulfur clusters: Nature's modular, multipurpose structures [J].

Beinert, H ;

Holm, RH ;

Munck, E .

SCIENCE, 1997, 277 (5326) :653-659

[23] STUDIES ON SUCCINIC AND DPNH DEHYDROGENASE PREPARATIONS BY PARAMAGNETIC RESONANCE (EPR) SPECTROSCOPY [J].

BEINERT, H ;

SANDS, RH .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1960, 3 (01) :41-46

[24] Aconitase as iron-sulfur protein, enzyme, and iron-regulatory protein [J].

Beinert, H ;

Kennedy, MC ;

Stout, CD .

CHEMICAL REVIEWS, 1996, 96 (07) :2335-2373

[25] 3-IRON CLUSTERS IN IRON SULFUR PROTEINS [J].

BEINERT, H ;

THOMSON, AJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1983, 222 (02) :333-361

[26] CRYSTAL-STRUCTURE OF [(C2H5)4N]3[FE4S4(SCH2PH)4], A REDUCED FERREDOXIN SITE ANALOG WITH A NONTETRAGONAL FE4S4 CORE STRUCTURE IN THE SOLID-STATE [J].

BERG, JM ;

HODGSON, KO ;

HOLM, RH .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1979, 101 (16) :4586-4593

[27]

BERG JM, 1982, IRON SULFUR PROTEINS, pCH1

[28] Crystal structure determination at 1.4 Å resolution of ferredoxin from the green alga Chlorella fusca [J].

Bes, MT ;

Parisini, E ;

Inda, LA ;

Saraiva, LM ;

Peleato, ML ;

Sheldrick, GM .

STRUCTURE WITH FOLDING & DESIGN, 1999, 7 (10) :1201-1211

[29] Structure of the mutant E92K of [2Fe-2S] ferredoxin I from Spinacia oleracea at 1.7 Å resolution [J].

Binda, C ;

Coda, A ;

Aliverti, A ;

Zanetti, G ;

Mattevi, A .

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY, 1998, 54 :1353-1358

[30] BASICITY OF THE SOLVENT AS THE MAIN FACTOR DETERMINING THE STABILITY OF [FE4S4(SR)4]- CLUSTER IONS IN SOLUTION [J].

BLONK, HL ;

KIEVIT, O ;

ROTH, EKH ;

JORDANOV, J ;

VANDERLINDEN, JGM ;

STEGGERDA, JJ .

INORGANIC CHEMISTRY, 1991, 30 (16) :3231-3234

← 1 2 3 4 5 6 7 8 9 10 →