Protein localization studies in the age of 'Omics'

被引：25

作者：

O'Rourke, NA

Meyer, T

Chandy, G

机构：

[1] Stanford Univ, Sch Med, Alliance Cell Signaling, Microscopy Lab, Stanford, CA 94305 USA

[2] Stanford Univ, Sch Med, Dept Mol Pharmacol, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 2005年 / 9卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.cbpa.2004.12.002

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

As thousands of new genes are identified in genomics efforts, the rush is on to learn something about the functional roles of the proteins encoded by those genes. Clues to protein functions, activation states and protein-protein interactions have been revealed in focused studies of protein localization. With technical breakthroughs such as GFP protein tagging and recombinase cloning systems, large-scale screens of protein localization are now being undertaken.

引用

收藏

页码：82 / 87

页数：6

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