Transformation of loganin and 7-deoxyloganin into secologanin by Lonicera japonica cell suspension cultures

被引:19
作者
Yamamoto, H [1 ]
Katano, N [1 ]
Ooi, Y [1 ]
Inoue, K [1 ]
机构
[1] Gifu Pharmaceut Univ, Dept Pharmacognosy, Gifu 502, Japan
关键词
Lonicera japonica; Caprifoliaceae; cell suspension cultures; iridoid glucoside; loganin; 7-deoxyloganin; secologanin; biosynthesis;
D O I
10.1016/S0031-9422(98)00613-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cell suspension cultures of Lonicera japonica used in this study did not produce ally iridoid and secoiridoid glucosides. However, the cells had the ability to convert loganin into secologanin. The cells also converted 7-deoxyloganin into both loganin and secologanin, but not geraniol into either iridoid glucoside or secologanin. In L. japonica cultured cells, the lack of the enzymes converting geraniol into iridoids might result in the non-production of secologanin. (C) 1998 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:417 / 422
页数:6
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