The use of celecoxib for reduction of pain after subpectoral breast augmentation

被引：42

作者：

Parsa, AA ^{[1
]}

Soon, CWM ^{[1
]}

Parsa, FD ^{[1
]}

机构：

[1] Univ Hawaii, John A Burns Sch Med, Dept Surg, Div Plast Surg, Honolulu, HI 96813 USA

来源：

AESTHETIC PLASTIC SURGERY | 2005年 / 29卷 / 06期

关键词：

breast implants; Celebrex; celecoxib; pain after breast surgery; pain and Subpectoral breast augmentation;

D O I：

10.1007/s00266-005-0032-1

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

A study was conducted to determine whether a single 400-mg dose of oral celecoxib administered 30 min before surgery reduces the opioid requirement for patients undergoing aesthetic subpectoral breast augmentation. A total of 695 patients undergoing breast augmentation were randomly selected into either a placebo or a treatment group. The findings showed that patients who received 400 mg of celecoxib 30 min before surgery required significantly fewer opioid analgesics after the operation than those given a placebo (p < 0.001). It also was found that nonsmokers and multiparous women required significantly fewer opioids than smokers and nulliparous women (p < 0.001). On the basis of this prospective study, the authors recommend a single 400-mg dose of celecoxib administered 30 min before surgery to decrease opioid analgesic requirements after subpectoral breast augmentation.

引用

页码：441 / 444

页数：4

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