The "Malaria's Eve" hypothesis and the debate concerning the origin of the human malaria parasite Plasmodium falciparum

被引：22

作者：

Su, XZ ^{[1
]}

Mu, JB ^{[1
]}

Joy, DA ^{[1
]}

机构：

[1] NIAID, Lab Malaria & Vector Res, NIH, Bethesda, MD 20892 USA

来源：

MICROBES AND INFECTION | 2003年 / 5卷 / 10期

关键词：

Malaria; evolution; TMRCA; genome diversity; single nucleotide polymorphism;

D O I：

10.1016/S1286-4579(03)00173-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The debate over whether the human malaria parasite Plasmodium falciparum underwent a recent severe population bottleneck ("Malaria's Eve" hypothesis) has attracted great attention recently. Understanding the genetic diversity and evolutionary history of the parasite has practical implications for developing disease control measures. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：891 / 896

页数：6

共 33 条

[1] Microsatellite markers reveal a spectrum of population structures in the malaria parasite Plasmodium falciparum [J].

Anderson, TJC ;

Haubold, B ;

Williams, JT ;

Estrada-Franco, JG ;

Richardson, L ;

Mollinedo, R ;

Bockarie, M ;

Mokili, J ;

Mharakurwa, S ;

French, N ;

Whitworth, J ;

Velez, ID ;

Brockman, AH ;

Nosten, F ;

Ferreira, MU ;

Day, KP .

MOLECULAR BIOLOGY AND EVOLUTION, 2000, 17 (10) :1467-1482

[2]

AYALA JA, 1998, MALARIA PARASITE BIO, P285

[3] RANDOM MATING IN A NATURAL-POPULATION OF THE MALARIA PARASITE PLASMODIUM-FALCIPARUM [J].

BABIKER, HA ;

RANFORDCARTWRIGHT, LC ;

CURRIE, D ;

CHARLWOOD, JD ;

BILLINGSLEY, P ;

TEUSCHER, T ;

WALLIKER, D .

PARASITOLOGY, 1994, 109 :413-421

[4]

Coluzzi M, 1999, PARASSITOLOGIA, VOL 41, NOS 1-3, SEPTEMBER 1999, P277

[5] High recombination rate in natural populations of Plasmodium falciparum [J].

Conway, DJ ;

Roper, C ;

Oduola, AMJ ;

Arnot, DE ;

Kremsner, PG ;

Grobusch, MP ;

Curtis, CF ;

Greenwood, BM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (08) :4506-4511

[6] Origin of Plasmodium falciparum malaria is traced by mitochondrial DNA [J].

Conway, DJ ;

Fanello, C ;

Lloyd, JM ;

Al-Joubori, BMAS ;

Baloch, AH ;

Somanath, SD ;

Roper, C ;

Oduola, AMJ ;

Mulder, B ;

Povoa, MM ;

Singh, B ;

Thomas, AW .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2000, 111 (01) :163-171

[7] Molecules on the surface of the Plasmodium falciparum infected erythrocyte and their role in malaria pathogenesis and immune evasion [J].

Craig, A ;

Scherf, A .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 115 (02) :129-143

[8] Malaria -: Cooperative silencing elements in var genes [J].

Deitsch, KW ;

Calderwood, MS ;

Wellems, TE .

NATURE, 2001, 412 (6850) :875-876

[9] Numerous potentially functional but non-genic conserved sequences on human chromosome 21 [J].

Dermitzakis, ET ;

Reymond, A ;

Lyle, R ;

Scamuffa, N ;

Ucla, C ;

Deutsch, S ;

Stevenson, BJ ;

Flegel, V ;

Bucher, P ;

Jongeneel, CV ;

Antonarakis, SE .

NATURE, 2002, 420 (6915) :578-582

[10] Selective pressures that decrease synonymous mutations in Plasmodium falciparum [J].

Forsdyke, DR .

TRENDS IN PARASITOLOGY, 2002, 18 (09) :411-417

← 1 2 3 4 →