Selective enrichment of anti-inflammatory drugs from river water samples by solid-phase extraction with a molecularly imprinted polymer

被引：37

作者：

Caro, E

Marcé, RM

Cormack, PAG

Sherrington, DC

Borrull, F

机构：

[1] Univ Rovira & Virgili, Dept Quim Analit & Quim Organ, Tarragona 43007, Spain

[2] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow, Lanark, Scotland

来源：

JOURNAL OF SEPARATION SCIENCE | 2005年 / 28卷 / 16期

关键词：

molecularly imprinted polymer; solid-phase extraction; ibuprofen; river water; cross-reactivity;

D O I：

10.1002/jssc.200500027

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A molecularly imprinted polymer (MIP) is synthesised by a noncovalent protocol in which ibuprofen was used as a template molecule. The polymer was evaluated chromatographically and it was seen that the MIP showed cross-reactivity. Subsequently, when this polymer was used as sorbent in SPE it was possible to selectively extract a mixture of nonsteroidal anti-inflammatory drugs from aqueous samples when a cleanup step with dichloromethane was performed. The performance of the MIP was evaluated with river water and water from a wastewater treatment plant, and compared with the performance of a commercial Isolute ENV+ sorbent.

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收藏

页码：2080 / 2085

页数：6

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