Revealing urologic diseases by proteomic techniques

被引：21

作者：

Lee, SW ^{[1
]}

Lee, KI

Kim, JY

机构：

[1] Chonnam Natl Univ, Sch Med, Genome Res Ctr Hematopoiet Dis, Kwangju 501746, South Korea

[2] Chonnam Natl Univ, Sch Med, Dept Anat, Kwangju 501746, South Korea

[3] Chonnam Natl Univ, Dept Ind Engn, Kwangju 500757, South Korea

[4] Korea Basic Sci Inst, Proteone Anal Team, Taejon 305333, South Korea

来源：

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES | 2005年 / 815卷 / 1-2期

关键词：

review; proteomics; urologic diseases;

D O I：

10.1016/j.jchromb.2004.11.008

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Proteomics, as the study of the proteomes of tissues and body fluids, has recently been introduced as a tool for revealing urologic diseases. Two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) and surface-enhanced laser desorption/ionzation (SELDI) are two techniques used in proteomic studies. Among the many urologic diseases, the malignancies including prostate cancer, bladder cancer, and renal cancer are the subjects most often selected for proteomic analysis. Poor reproducibility is one of the difficulties that must be overcome in order for proteomic technology to be a robust tool. (C) 2004 Elsevier B.V. All rights reserved.

引用

页码：203 / 213

页数：11

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